Journal Articles

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Antioxidant Synergy of Mitochondrial Phospholipase PNPLA8/iPLA2γ with Fatty Acid-Conducting SLC25 Gene Family Transporters Antioxidants   PDF

Developmental window of vulnerability to white matter injury driven by sublethal intermittent hypoxemia Pediatric Research   PDF

Rats with Human Mutation of NFU1 Develop Pulmonary Hypertension American Journal of Respiratory Cell and Molecular Biology   PDF

Measurement of mitochondrial H2O2 production under varying O2 tensions Methods in Cell Biology   155, 273-293. PDF

Hypothermic oxygenated perfusion protects from mitochondrial injury before liver transplantation EBioMedicine   2020 PDF

Cyclophilin D-dependent oligodendrocyte mitochondrial ion leak contributes to neonatal white matter injury Journal of Clinical Investigation   PDF

Partial inhibition of mitochondrial complex I ameliorates Alzheimer’s disease pathology and cognition in APP/PS1 female mice Communications Biology   4, 61. PDF

Water route for proton pumping in mitochondrial complex I Nature Structural & Molecular Biology   PDF

Deactivation of mitochondrial complex I after hypoxia-ischemia in the immature brain Journal of Cerebral Blood Flow & Metabolism   271678X18770331. PDF

The dependence of brain mitochondria reactive oxygen species production on oxygen level is linear, except when inhibited by antimycin A Journal of Neurochemistry   148, 731-745. PDF

Redox-dependent loss of flavin by mitochondrial complex I in brain ischemia/reperfusion injury Antioxidants & Redox Signaling   31, 608-622. PDF

Distal denervation in the SOD1 knockout mouse correlates with loss of mitochondria at the motor nerve terminal Experimental Neurology   318, 251-257. PDF

Redox Signaling Through Compartmentalization of Reactive Oxygen Species: Implications for Health and Disease Antioxidants & Redox Signaling   31, 591-593 PDF

Mechanism of mitochondrial complex I damage in brain ischemia/reperfusion injury. A hypothesis Molecular and Cellular Neuroscience   100, 103408. PDF

Brain Ischemia/Reperfusion Injury and Mitochondrial Complex I Damage Biochemistry   84, 1411-1423. PDF

Krebs cycle metabolites and preferential succinate oxidation following neonatal hypoxic-ischemic brain injury in mice Pediatric Research   83, 491-497. PDF

Critical role of flavin and glutathione in Complex I-mediated bioenergetic failure in brain ischemia/reperfusion injury Stroke   49, 223-1231. PDF

Attenuation of oxidative damage by targeting mitochondrial complex I in neonatal hypoxic-ischemic brain injury Free Radical Biology and Medicine   124, 517-524. PDF

Leigh Syndrome Mouse Model Can Be Rescued by Interventions that Normalize Brain Hyperoxia, but Not HIF Activation Cell Metabolism   PDF

Ischemic A/D transition of mitochondrial complex I and its role in ROS generation Biochimica et Biophysica Acta   1857, 946-957. PDF

Differential susceptibility of mitochondrial complex II to inhibition by oxaloacetate in brain and heart Biochimica et Biophysica Acta   1857:1561-1568. PDF

Modulation of the conformational state of mitochondrial complex I as a target for therapeutic intervention Interface Focus   7:20160104. PDF

Neurotoxic mechanisms by which the USP14 inhibitor IU1 depletes ubiquitinated proteins and Tau in rat cerebral cortical neurons: relevance to Alzheimer’s disease Biochimica et Biophysica Acta   1863:1157-1170. PDF

HLA gene and haplotype frequencies in a Nagaybaks population from the Chelyabinsk Region (Russian South Urals) Human Immunology   78:595-601. PDF

Distinct intracellular sAC-cAMP domains regulate ER calcium signaling and OXPHOS function Journal of Cell Science   130:3713-3727. PDF

Early cerebellar deficits in mitochondrial biogenesis and respiratory chain complexes in the KIKO mouse model of Friedreich ataxia Disease Models & Mechanisms   10:1343-1352. PDF

Reverse electron transfer results in a loss of flavin from mitochondrial complex I. Potential mechanism for brain ischemia/reperfusion injury Journal of Cerebral Blood Flow & Metabolism   271678 X 17730242. PDF

Packaging and transfer of mtDNA via exosomes regulate escape from dormancy in hormonal therapy resistant breast cancer Proceedings of the National Academy of Sciences of the United States of America   114:E9066-E9075. PDF

Characterisation of the active/deactive transition of mitochondrial complex I Biochimica et Biophysica Acta   1837:1083-1092. PDF

ND3, ND1 and 39 kDa subunits are more exposed in the de-active form of bovine mitochondrial complex I Biochimica et Biophysica Acta   1837:929-939. PDF

A potential of siRNA technology in kidney transplantation BioDrugs   28:345-361. PDF

Effect of monovalent cations on the kinetics of hypoxic conformational change of mitochondrial complex I Biochimica et Biophysica Acta   1847:1085–1092. PDF

The evaluation and quantitation of dihydrogen metabolism using deuterium isotope in rats PLOS One   10:e0130687. PDF

Variation in oxygen consumption among ‘living fossils’ (Mollusca: Polyplacophora) Journal of the Marine Biological Association of the United Kingdom   93, 197–207. PDF

Conformational change of mitochondrial complex I increases ROS sensitivity during ischaemia Antioxidants & Redox Signaling   19, 1459-68. PDF

Conformation-specific crosslinking of mitochondrial complex I FEBS Letters   587:867-872. PDF

Molecular mechanism and physiological role of active-deactive transition of mitochondrial complex I Biochemical Society Transactions   41:1325-1330. PDF

Preparation of Highly Coupled Rat Heart Mitochondria Journal of Visualized Experiments   PDF

The redox-Bohr group associated with iron-sulfur cluster N2 of complex I Journal of Biological Chemistry   281:23013-23017. PDF

The proton pumping stoichiometry of purified mitochondrial complex I reconstituted into proteoliposomes Biochimica et Biophysica Acta   1757:1575-1581. PDF

Nitric oxide and hypoxia Essays in Biochemistry   43: 29-40. PDF

Nitrosation of mitochondrial complex I Journal of Biological Chemistry   282: 37448-37453. PDF

Identification of the mitochondrial complex I ND3 subunit as a structural component involved in the active/de-active enzyme transition Journal of Biological Chemistry   283: 20907-20913. PDF

Measurement of superoxide formation by mitochondrial complex I of Yarrowia lipolytica Methods in Enzymology   456: 475-490. PDF

Lack of oxygen deactivates mitochondrial complex I: Implications for ischemic injury? Journal of Biological Chemistry   284: 36055-36061. PDF

Stoichiometry of the NADH:Ubiquinone reductase reaction catalyzed by mitochondrial Complex I Biochemistry (Moscow)   66:435-537. PDF

Dendritic porphyrins and tetrabenzoporphyrins: tunable membrane-impermeable fluorescent pH sensors Journal of the American Chemical Society   125:4882 – 4893. PDF

HDQ (1-hydroxy-2-dodecyl-4(1H)-quinolone), a high affinity inhibitor for mitochondrial alternative NADH-dehydrogenase – evidence for a ping-pong mechanism Journal of Biological Chemistry   280:3138-3142. PDF

Structure-function relationship in mitochondrial complex I of the strictly aerobic yeast Yarrowia lipolytica Biochemical Society Transactions   33:840-844. PDF

Superoxide radical formation by pure complex I (NADH: Ubiquinone oxidoreductase) from Yarrowia lipolytica Journal of Biological Chemistry   280:30129-30135. PDF

Proton pumping by complex I (NADH:ubiquinone oxidoreductase) from Yarrowia lipolytica reconstituted into proteoliposomes Biochimica et Biophysica Acta   1710:87-95. PDF

Stoichiometry in NADH-quinone reductase reactions catalyzed by the bovine heart submitochondrial particles FEBS Letters   451:157-161. PDF